Solanum
nodiflorum Jacq. Var. macrophyllum Dunal
Solanum
rubrum Nees
Local
names: Amti (Bon., If.); anti
(Bon., Tag.); bolagtab (Bis.); gamagamatisan (Tag.); hulablub
(Bis.); kamkamatisan (Tag.); kamatesmanuk (S. L. Bis.); konti (Tag.); kuti (Bik.); lagkakum
(Bis.); lubi-lubi (Tag., Bik., Bis.); malasili (S. L. Bis.); muti
(Sul., Bik.); natang-ni-aso (Ig.); nateng (Iv.); onti (Tag.);
black nightshade, deadly nightshade, garden or common nightshade (Engl.).
Lubi-lubi
us found throughout the Philippines in open, waste places, recently disturbed
soil, etc., from sea level to an altitude of 2,000 meters. It is cosmopolitan.
This is an
erect, branched, smooth or nearly smooth herb 1 meter or less in height. The stems are green and somewhat
3-angled. The leaves are ovate to
oblong, 5 to 8 centimeters long, and pointed at both ends, with subentire or
undulately toothed or lobed margins. The
flowers are umbellately toothed or lobed margins. The flowers are umbellately disposed, 5 to 8 on each peduncle,
nodding, and borne on extra-axillary in inflorescences 1 to 2.5 centimeters
long. The calyx is green, with
ovate-oblong lobes. The corolla is
white, and about 8 millimeters in diameter.
The fruit (berry) is dark purple or black, smooth, shining, rounded, and
about 5 millimeters in diameter. The
seeds are yellow and minutely pitted.
The fruit
of the improved variety is edible in the Philippines. Ripe, it makes delightful jam and excellent pies. Watt and Breyer-Brandwijk say that the Sutos
use the young shoots as spinach and that the leaves, after boiling in water,
are eaten as a vegetable in the Isle of France, Bourbon Island, and the
Hawaiian Islands. Hooper states that the
Bote women use the fruit as a cosmetic; they rub the fresh seeds on their
cheeks to remove freckles that it is widely eaten in Africa and are a favorite
vegetable in Mauritius.
Desfosses
isolated in 1821 from the fruit, solanine.
In 1891 Schmidt and Schutle isolated from the leaves a trace of an
unidentified, mydriatic alkaloid; and in 1892 Waage isolated saponins from the
fruit. Kobert reports that in addition
to solanine, the plant contains a tropeine alkaloid with a mydriatic action. Martinez cites Professor Cordero, who
conducted a chemical analysis of the plant without fruit:
|
Fats and chlorophyll |
0.795 |
|
Resin (neutral) |
0.357 |
|
Tannic acid |
0.006 |
|
Resin (acid) |
3.402 |
|
Cellulose |
65.930 |
|
Gummy principles |
0.471 |
|
Glucose |
1.705 |
|
Mineral salts |
10.140 |
|
Alkaloid |
----------- |
|
Moisture and undosified
substances |
17.94 |
|
An
analysis of the fruit by Professor Cordero follows: |
|
|
Fats acids and chlorophyll |
13.47 |
|
Resin (acid) |
1.95 |
|
Resin (neutral) |
0.39 |
|
Tannic acid |
8.42 |
|
Glucose |
0.05 |
|
Gummy principles |
3.01 |
|
Dextrine and allied substances |
0.39 |
|
Coloring matter |
0.11 |
|
Alkaloid |
no
dosification |
|
Cellulose |
53.49 |
|
Ash |
6.70 |
|
Moisture |
12.02 |
Analyses
of the fruit of the large, cultivated variety grown in the Philippines show
that they are an excellent source of calcium and phosphorus and a good source
of iron.
The plant
is official in the Portuguese (3) Pharmacopoeia; the leaves in the Belgian (2);
Danish (1,2); French (1-5); Greek (3); Mexican (1-4); Spanish (1-7); Swedish
(1-4); and Venezuelan (1,2) Pharmacopoeias; and the fruit in the Spanish (1,2)
Pharmacopoeias.
Regarding
the toxicity of the plant, Steyn mentions Kobert, Pammel, Kannigesser and
Leffkowitz, who describe poisoning in human beings who have partaken of the
fruit. Steyn, however, remarks that as the fruit matures, it gradually
decreases in toxicity until, when ripe, it contains no more, or perhaps more
correctly, only nontoxic amounts of solanin. The harmlessness of the mature
fruit is evidenced by the fact that it is extensively eaten, especially by
children. It is also used in the making of jam and, instead of resins, in the
making of puddings. Tavera mentions that the plant is narcotic and
antispasmodic and that, like belladonna, it dilates the pupil. According to
Watt and Breyer-Brandwijk the action of the active principle is similar to that
of the saponins, but much less toxic. Clinically, the symptoms of poisoning are
vomiting and diarrhea, accompanied by headache and colic, and followed by
depression.
Kannigiesser
reports that the effect of nightshade berries on the eyes was observed ½ hour
after ingestion; mydriasis reached a maximum after 6 hours; and restriction of
accommodation continued for 50 hours. The pulse was unchanged and the amount of
urine was somewhat decreased. Subacute dryness of the throat was experienced
after 1¾ hours; this persisted for 50 hours. Diminished secretion of sweat with
dryness of the skin, mouth, larynx, and esophagus was observed. The skins of
the berries were excreted unchanged in the feces after 49 hours. Bade suggests
that in every case of poisoning a doctor must be called. In the meantime, until
he arrives, it is advisable to give an emetic, and tannin or a liquid
containing tannin. Artificial respiration may be used to counteract a possible
paralysis of the lungs.
In the
Philippines the fruit is reputed, to be a cure for diabetes, as eating them
freely tends to reduce the sugar in the blood. According to Guerrero the
leaves, when prepared in poultices, are said to have sedative and healing
properties. Prepared as an alcoholate, they are said to alleviate neuralgic
pains.
According
to Standley, in Sinaloa the roots are said to have been employed as a remedy
for bubonic plague.
Standley
says that a decoction of the plant is employed as a fomentation for sore-eyes
and for various skin diseases. Stuart states that the young shoots are eaten,
after boiling and are considered to be corrective, cooling, and tonic to men
(increasing virility) and women (benefiting menstrual disorders). The stalk,
leaves, and root are used in decoction for wounds and cancerous sores, and as
an astringent. They are also thought to have diuretic properties. Kirtikar and
Basu report that the Chinese employ the juice of the leaves to alleviate the
pain in inflammation of the kidneys and bladder and in virulent gonorrhoea. Burkill
and Haniff record the uses of a decoction as a lotion for yaws. Watt and
Breyer-Brandwijk write that the Zulus administer an infusion as an enema to
infants with abdominal upsets. The Sutos rub the burnt and powdered root into
incisions in the back for the relief of lumbago. They quote Hewat, who states
that the plant is one of the native remedies for local application to anthrax
pustules, and that natives apply a paste of the green berries to ringworm.
Mixed with honey, it is sometimes administered to people suffering from
pulmonary tuberculosis. According to Steyn, in South Africa the expressed juice
of the herb, and its decoction, are often successfully employed in cleaning and
healing foul ulcers. He states that the plant is used in the treatment of headaches.
He quotes Dragendorff, who states that the plant is used internally as a
diuretic and an emetic. He also quotes Dornan, who says that the Rhodesian
natives use the plant in the treatment of malaria, black water fever, and
dysenteries.
Martinez
reports that in Mexico a decoction of the plant is applied externally as a
cooling agent, as a vulnerary (in the
form of fomentations), and for vaginal irrigation.
Nadkarni
asserts that the leaves are employed as a poultice over rheumatic and gouty joints
and also as a remedy in skin diseases. A fluid extract of the leaves and stems
has been recommended in dropsy, in doses of ½ to 2 drachms; also in heart
diseases, skin diseases, piles, gonorrhoea, inflammatory swellings, and chronic
enlargement of the liver and spleen. A syrup of it is useful as a cooling drink
in fevers, and to promote perspiration. The heated leaves are applied to
painful and swollen testicles. Rolet and Bouret state that in Bohemia the
leaves are placed in the cradles of infants to induce sleep. Standley says that
the leaves are sometimes applied as a poultice to allay pain.
Standley reports that in Mexico the fruit is a domestic remedy for erysipelas. Steyn says that a paste of the immature fruit is used in the treatment of ringworm. Kirtikar and Basu remark that in Hindu medicine the berries are tonic, diuretic, and useful in anasarca and heart diseases. In Bengal the berries are employed in fever, diarrhea, eye diseases, hydrophobia, etc. A decoction of the berries and flowers is said to be useful in coughs, and consumption, in doses of 1 to 2 ounces.